Crosslinking of DNA and RNA to nylon or nitrocellulose membranes
Microprocessor control provides precise UV dose control
Irradiation can be defined as energy (Joules/cm²) or time (seconds)
- Preset programs for nucleic acid immobilization at 120 mJoule/cm2
- Safety interlock door with UV protection glass
Shortwave UV (UVC) as a Disinfectant
Ultraviolet light is considered an ancillary disinfectant to chemical disinfectants in the healthcare environment. Our high-precision CL-3000 crosslinker is capable of producing a cumulative dosage of 1 J/cm2 , this is considered well beyond the requirement needed for disinfection. The CL-3000 provides nearuniform UVC light with a ~10% coefficient of variation and less than 2 mJ/cm2 difference between the highest and lowest reading. Most importantly, the CL-3000 has real-time monitoring of UVC dosage to assure reproducible dosing irrespective of space and time.
Immobilization of Nucleic Acids to Membranes
The UVP Crosslinker is a microprocessor controlled UV irradiation system dedicated to nucleic acid linking to membranes for Southern, Northern, Dot and Slot Blot applications. It can also be used for UV disinfection and for elimination of PCR contaminations.
Microprocessor Controlled Reproducibility
The programmable microprocessor constantly monitors the UV light emission. Irradiation stops exactly when the programmed energy is achieved. Thus, the effect of decreasing UV intensity due to bulb aging is compensated for.
The UVP Crosslinker combines the latest UV technology with high quality manufacturing: aluminum UV exposure chamber, protective quartz disk on the UV sensor cell, and a highly resistant and easy-to-clean keypad and housing.
Ease of use
The large display provides a series of predefined methods, making the UVP Crosslinker an easy to use yet powerful instrument for immobilization of nucleic acids to membranes. The programmed data are shown on the LED display.
Legacy UVP Crosslinkers
Legacy UVP Crosslinker CL-1000 orders starting April 20th, 2020, will be upgraded to the new CL-3000 Crosslinker. For customers requiring the CL-1000 version exclusively, please contact customer service. Service and spare parts for UVP Crosslinker CL-1000, CL-1000M, and CL-1000L will be available and offered for 5 years from discontinuation date (April 20th, 2025).
6 x 8W 254 nm or 365 nm
UV irradiation energy
|0.1 mJ/cm2 to 9999.9 mJ/cm2|
Maximum time of exposure
|22.2 x 40.0 x 34.9|
Chamber (inside) dimensions
12.7 x 30.5 x 25.4
Legacy UVP Crosslinker CL-1000 available here
|115 V||230 V||Description||Wavelength|
|849-95-0615-01||849-95-0615-02||UVP Crosslinker CL-3000||254 nm|
|849-95-0615-03||849-95-0615-04||UVP Crosslinker CL-3000M||302 nm|
|849-95-0615-05||849-95-0615-06||UVP Crosslinker CL-3000L||365 nm|
|Replacement UV tube, 8 Watt, 254 nm|
|34-0042-01 (US)||Replacement UV tube, 8 Watt, 302 nm|
|34-0006-01 (US)||Replacement UV tube, 8 Watt, 365 nm|
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